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Barry Schuler Genomics 101

It's kind of like genomics.

I got interested in gene sequencing.

Fulfilling the Genomic Promise

Richard Resnick Welcome to the genomic revolution

It's called the Beijing Genomics Institute.

Juan Enriquez on genomics and our future

DNA sequencing on your iPhone? There's an app for that.

We live in in a remarkable time, the age of genomics.

In fact, it's not a genomically literate world.

This is the genomic revolution today. This is where we are.

Guys, this would never have happened without whole genome sequencing.

I first met him through the Archon X PRIZE for Genomics.

But remember, I'm not pushing genomics, proteomics, to be a reductionist.

But that is changing rapidly with the aid of new genomic technology.

That is the genomically literate world. And that is a problem.

There's no molecular test, there's no sequencing of genes that was referred to yesterday, there's no fancy looking at the chromosomes.

What is genomics? How will it affect our lives? In this intriguing primer on the genomics revolution, entrepreneur Barry Schuler says we can at least expect healthier, tastier food. He suggests we start with the pinot noir grape, to build better wines.

And in both cases, we were able to use genetic sequencing to look at the polio viruses, and we could tell these viruses were not from these countries.

In addition to genomic information such as sequences, all information, including structural, metabolic, and reproductive features, should be included in the description.

Except genomics is a lens on biology through the window of the sequence of bases in the human genome.

And it's fair to say that in these 10 years, we've witnessed absolutely the start of a scientific revolution that of genome medicine.

If we understand biology from genomics and omics and wireless through physiologic phenotyping, that's big.

In this accessible talk from TEDxBoston, Richard Resnick shows how cheap and fast genome sequencing is about to turn health care upside down.

And so I urge you all to wake up and to tune in and to influence the genomic revolution that's happening all around you.

The particular data Pachter used was collected by researchers at the Caribbean Genome Center at the University of Puerto Rico in Mayagüez.

The US continues to excel, with huge recent breakthroughs in Mars exploration and genomics, though it is now imperiling that excellence through budget cuts.

As the American Museum of Natural History provocatively asked at the 2001 opening of its genetics exhibition The genomic revolution is here are you ready?

This is a project that had its inception 15 years ago when our team then we called the institute TIGR was involved in sequencing the first two genomes in history.

The U.S. Library of Congress, in terms of its printed volume of data, contains less data than is coming out of a good genomics company every month on a compound basis.

Let me say that again A single genomics company generates more data in a month, on a compound basis, than is in the printed collections of the Library of Congress.

What's happening in genomics, and how this revolution is about to change everything we know about the world, life, ourselves, and how we think about them.

More recently, government and industry got together to cut the costs of sequencing an individual genome from around 100 million in 2001 to just 1,000 today.

Craig Venter has just joined our board and we're doing a rapid genome sequencing prize with him, we'll be announcing later this fall, about imagine being able to sequence anybody's DNA for under 1,000 dollars, revolutionize medicine.

But because each of your cells contains your entire gene code, each cell can be reprogrammed, if we don't stop stem cell research and if we don't stop genomic research, to express different body functions.

For example, efforts to sequence the genome of the gray mouse lemur will help researchers understand which genetic traits set primates apart from other mammals and will ultimately help understand what genomic traits set humans apart from other primates.

Scientific discoveries, futurist Juan Enriquez notes, demand a shift in code, and our ability to thrive depends on our mastery of that code. Here, he applies this notion to the field of genomics.

Genomics pioneer Craig Venter takes a break from his epic round the world expedition to talk about the millions of genes his team has discovered so far in its quest to map the ocean s biodiversity.

Taras Oleksyk, one of the researchers involved in collecting the data, explained Pachter's thought experiment in a nutshell in a post published on the Caribbean Genome Center's blog a few days after Pachter's post went viral

Around the turn of the century, the first sequencing of the human genome led to reverse vaccinology. This approach, whereby computational analysis of a pathogen s genome enables identification and screening of a great many more potential vaccine targets than was previously possible, was used in the successful development of a vaccine against meningitis B.

Likewise, the dramatic reduction in the cost of gene sequencing, from roughly 40 million per human genome in 2003 to about 5,000 today, together with a rapid increase in computational power, is boosting the speed, accuracy, and robustness of medical diagnostic tests.

First, major advances in our knowledge of genomics specifically, the way diseases manifest and develop in the body at the genetic level are improving our ability to target illness at each stage and improve the patient experience.

To this end, the collaboration of social and scientific institutions would help to break down language and cultural barriers, ensuring that the genomic revolution aids, rather than alienates, the public, and thereby passes the true test of any scientific advancement relevance to everyday experience.

Within a short while, I think there's going to be a new field called Combinatorial Genomics, because with these new synthesis capabilities, these vast gene array repertoires and the homologous recombination, we think we can design a robot to make maybe a million different chromosomes a day.